S S Madkar, Ashok Jaykumar Vankudre, SL Nilekar


Aim: AIDS is characterized by a number of opportunistic infections which are responsible for high morbidity and mortality. The spectrum and distribution of opportunistic infections (OIs) in AIDS patients is ever-expanding. This spectrum varies from continent to continent. The aim of the present study was to document the spectrum of OIs in HIV-infected patients in Ambajogai. Material and Method: 178 HIV positive symptomatic patients, either hospitalized or coming to ART (Antiretroviral Therapy) centre in S.R.T.R. Medical College, Ambajogai, were included in the study for finding the spectrum of opportunistic infections. Result: The commonest opportunistic infection seen was tuberculosis (59% of patients), followed by oral candidiasis (37.6% of patients) and parasitic diarrhea due to Cryptosporidium parvum(18 % of patients). It was observed that out of 178 patients, maximum 53.3% were in the age group of 29-38 years followed by 21% in the age group of 39-48 years. It was found that 77% were males and 23% were females, with male to female ratio is 3.3:1. Conclusion: This study demonstrates that tuberculosis is the commonest opportunistic infection seen in HIV patients. Clinicians should consider HIV in the differential diagnosis and management of all persons with tuberculosis.


Opportunistic Infections, tuberculosis, candidiasis, male, female

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K. Park, editor. AIDS. In: Park’s textbook of preventive and social medicine, 20th ed, M/s Banarsidas Bhanot Publisher. 2009; P.298-310.

National AIDS Control Organization, Ministry of Health and Family Welfare, Govt. of India. Section 1. Introduction. In: Guidelines for prevention and management of common opportunistic infections/Malignancies among HIV infected Adults and Adolescents. New Delhi; 2008: P.1-3.

Chakraborty N, Mukherjee A, Santra S et al. Current trends of opportunistic infections among HIV-seropositive patients from Eastern India. Jpn. J. Infect. Dis. 2008; 61: 49-53.

Singh A, Bairy I, Shivananda PG. Spectrum of opportunistic infections in AIDS cases. Indian J Med science. 2003; 57(1): 16-21.

Sharma SK, Kadhiravan T, Banga A et al. Spectrum of clinical disease in a series of 135 hospitalized HIV-infected patients from North India. BMC infect. Dis. 2004; 4: 52.

Chakravarty J, Mehta H, parekhA, et al. Study on clinco-epidemiological profile of HIV patients in Eastern India. JAPI. Nov. 2006; 54: 854-857.

Kumaraswamy N, Solomon S, Jayaker Paul SA et al.Spectrum of opportunistic infections among AIDS patients in Tamil Nadu, India. Int J STD AIDS. 1995; 6: 447-449.

Zaheer MS, Rabbani MU, Zuber A et al. Clinical and Demographic profile of patients of AIDS in and around Aligarh. JIACM. 2003; 4(2): 121-26.

Gupta V, Singla N, Lehl S S, Chander J.Clinico- epidemiological profile of HIV infection over a period of six years in a North Indian tertiary care hospital. IJMM . 2007; 25(2): 171.

Uzgare R. Mode of transmission of HIV in Mumbai (India) as per data collected in a private HIV/AIDS clinic. IntConf AIDS. 2000 Jul 9-14; 13: abstract no. TuPeC3369.

Kothari K, Goyal S. Clinical profile of AIDS. JAPI. 2001 Apr; 49: 435-8.

Kumar P, Sharma N, Sharma N C et al. Clinical profile of tuberculosis in patients with HIV infection/AIDS. The Indian Journal of chest Diseases and Allied science. 2002; 44(3): 159-63.

Rani NU, Reddy VVR, Kumar AP et al. Clinical Profile of Pneumocystis Carinii Pneumonia In HIV Infected Persons. Ind. Journal of tuberculosis. 2000; 47: 93-6.

Jyotirmay B, Amala J, Raizadaseemant et al. Ophthalmic manifestations of human immunodeficiency virus (HIV) infection in India. Indian J ophthalmology. 1999; 47: 87-93.

Vajpayee M, Kanswal S, Seth P, Wig N. Spectrum of opportunistic infections and profile of CD4+ counts among AIDS patients in North India. 2003 oct; 31(5): 336-40.

Sinha S, Guleria R. Spectrum of Pulmonary infections in HIV positive patients: Indian scenario. HIV Related lung Disease. October 27, 2004; Ref No. 109.

Kumarasamy N, Solomon S, Madhivanan P et al. Dermatologic manifestations among human immunodeficiency virus patients in South India. International Journal of Dermatology. 2000; 39(3): 192-5.

Wadhwa A, Kaur R, Agarwal SK et al. AIDS- related opportunistic mycoses seen in a tertiary care hospital in North India. Journal of Medical Microbiology. 2007; 56: 1101-1106.

Sauda FC et al. Prevalence of Cryptosporidium species and Isospora belli among AIDS patients attending Santos Reference center for AIDS, S ao Paulo, Brazil. J. Parasitol. 1993; 79(3): 454-56.

Ghorpade MV, Kulkarni SA, Kulkarni AG. Cryptosporidium, Isospora and strongyloides in AIDS. Natl Med. J. India. 1996; 9(4): 201.

Mohandas, Sehgal R, Sud A, Malla N. Prevalence of intestinal parasitic pathogens in HIV–seropositive individuals in Northern India. Jpn J.Infect.Dis. 2002; 55(3): 83-4.

Guk SM, Seo M, Park YK et al. Parasitic infections in HIV-infected patients who visited Seoul National University Hospital during the period 1995-2003.The Korean J. Parasitol. 2005 Mar; 43(1): 1-5.


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