EFFECT OF TURMERIC (CURCUMA LONGA) ON OVERWEIGHT HYPERLIPIDEMIC SUBJECTS: DOUBLE BLIND STUDY

Published

2012-06-30

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Original Article

Authors

  • Lekhani Pashine
  • J V Singh
  • A K Vaish
  • S K Ojha
  • A A Mahdi

Abstract

Objective: To evaluate the effect of turmeric (Curcuma longa) on serum lipid profile in overweight hyperlipidemic subjects. Methods: This was a double blind randomised control study. The study was conducted in the Department of Medicine, CSM Medical University, Lucknow from July 2010-June 2011. A total of 120 subjects were interviewed using a pre-tested semi-structured schedule whose BMI>25 and total cholesterol>200 mg/dl and/or triglyceride>150 mg/dl, were divided randomly using random number table into 2 groups Group-I (Aquous extract of Turmeric-1.4 gm per day) (n=53) and Group-II (Placebo) (n=52) for three months. They were given the same color capsules without revealing their identity, with the instructions to take the contents of each pack twice a day before meal for 90 days. Subjects were asked to give their 12 hour fasting blood samples on 0, 30, 60 and 90 day. The paired t-test was used to compare the changes amongst follow-ups and unpaired t-test was used to compare between groups. p-value<0.05 was considered as significant. Results: At the baseline, both the groups were similar in anthropometric and clinical parameters. Treatment group produced significant (p<0.0001) reduction in lipid profiles such as serum total cholesterol, triglyceride and LDL-cholesterol and VLDL- cholesterol in hypercholesteremic group from 0 day to 30, 60 and 90 day of follow-ups. However, there was no significant change in the placebo group. The percentage reduction was higher in the subjects of Turmeric group as compared to Placebo. Conclusion: Aquous extract of Turmeric has shown lipid lowering properties among overweight hyperlipidemic subjects.

How to Cite

1.
Pashine L, Singh JV, Vaish AK, Ojha SK, Mahdi AA. EFFECT OF TURMERIC (CURCUMA LONGA) ON OVERWEIGHT HYPERLIPIDEMIC SUBJECTS: DOUBLE BLIND STUDY. Indian J Community Health [Internet]. 2012 Jun. 30 [cited 2022 Nov. 26];24(2):113-7. Available from: https://www.iapsmupuk.org/journal/index.php/IJCH/article/view/233

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