Statistical Modelling for the Assessment of Low Birth Weight in Tertiary Care Settings (2019-2024)

Authors

DOI:

https://doi.org/10.47203/IJCH.2025.v37i05.004

Keywords:

Low Birth Weight, Statistical Model, Logistic Regression, Machine Learning, Multiple linear Regression, Bayesian Method, Structural Equation Modeling

Abstract

LBW is a major public health concern worldwide, particularly in developing countries, and is defined as a birth weight of less than 2,500 grams. It is essential to properly evaluate and manage LBW infants because this practice minimizes newborn health complications. This analysis reviews the application of statistical models (2019-2024) which evaluate risk components and treatment results for LBW cases found in tertiary medical facilities. Research uses logistic regression along with machine learning models in accord to survival analysis to discover maternal indicators alongside clinical indicators & socioeconomic indicators that predict LBW. Multiple risk factors are successfully integrated through advanced learning approaches starting from classical regression methods as the review demonstrates. Findings suggest that ensemble methods and deep learning models demonstrate superior predictive performance compared to conventional statistical approaches. The studies indicate that integrating machine learning methods with traditional biostatistics offers a more nuanced understanding of LBW risk. However, the need for interpretable models in clinical settings remains paramount.

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References

Okwaraji YB, Bradley E, Ohuma EO, Yargawa J, Suarez-Idueta L, Requejo J, et al. National routine data for low birthweight and preterm births: systematic data quality assessment for United Nations member states (2000–2020). BJOG. 2024;131(7):917-928.

Mukosha M, Jacobs C, Kaonga P, Musonda P, Vwalika B, Lubeya MK, et al. Determinants and outcomes of low birth weight among newborns at a tertiary hospital in Zambia: a retrospective cohort study. Ann Afr Med. 2023;22(3):271-278.

Liu Z, Han N, Su T, Ji Y, Bao H, Zhou S, et al. Interpretable machine learning to identify important predictors of birth weight: a prospective cohort study. Front Pediatr. 2022;10:899954.

KC A, Basel PL, Singh S. Low birth weight and its associated risk factors: health facility-based case-control study. PLoS One. 2020;15(6):e0234907.

Gupta S, Jatav P, Saroshe S, Shukla H, Bansal SB. A cross-sectional study to assess factors affecting low birth weight at tertiary care center, Indore. Indian J Public Health Res Dev. 2024;15(3):[pages].

Christian P, West KP Jr, Khatry SK, LeClerq SC, Pradhan EK, Katz J, et al. Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal. Am J Clin Nutr. 2003;78(6):1194-1202.

Thapa P, Poudyal A, Poudel R, Upadhyaya DP, Timalsina A, Bhandari R, et al. Prevalence of low birth weight and its associated factors: hospital-based cross-sectional study in Nepal. PLOS Glob Public Health. 2022;2(11):e0001220.

Mondal B. Risk factors for low birth weight in Nepali infants. Indian J Pediatr. 2000;67:477-482.

Islam MJ, Chowdhury MH, Rahman MM, Rahman Z. Risk factors of children’s low birth weight and infant mortality in Bangladesh: evidence from binary logistic regression and Cox PH models. Health Sci Rep. 2024;7(8):e70009.

Borson NS, Kabir MR, Zamal Z, Rahman RM. Correlation analysis of demographic factors on low birth weight and prediction modeling using machine learning techniques. In: Proc 4th World Conf Smart Trends Syst Secur Sustain (WorldS4); 2020 Jul 27; India. IEEE; 2020. p. 169-173.

Ranjbar A, Montazeri F, Farashah MV, Mehrnoush V, Darsareh F, Roozbeh N. Machine learning-based approach for predicting low birth weight. BMC Pregnancy Childbirth. 2023;23(1):803.

Wang Q, Gao W, Duan Y, Ren Z, Zhang Y. Exploring predictors of interaction among low-birth-weight infants and their caregivers: a machine learning-based random forest approach. BMC Pediatr. 2024;24(1):648.

Avwerhota OO, Avwerhota M, Daniel EO, Popoola TA, Popoola IO, Ogun AA, et al. Bayesian spatial analysis of risk factors affecting low birth weight in Nigeria. J Fam Med Health Care. 2024;10(3):40-50.

Maniragaba VN, Atuhaire LK, Rutayisire PC. Modeling the risk factors of undernutrition among children below five years of age in Uganda using generalized structural equation models. Children (Basel). 2023;10(12):1926.

Patterson JK, Thorsten VR, Eggleston B, Nolen T, Lokangaka A, Tshefu A, et al. Building a predictive model of low birth weight in low- and middle-income countries: a prospective cohort study. BMC Pregnancy Childbirth. 2023;23(1):600.

Arabzadeh H, Doosti-Irani A, Kamkari S, Farhadian M, Elyasi E, Mohammadi Y. The maternal factors associated with infant low birth weight: an umbrella review. BMC Pregnancy Childbirth. 2024;24(1):316.

Bhagat AK, Mehendale AM, Muneshwar KN, Bhagat A. Factors associated with low birth weight among the tribal population in India: a narrative review. Cureus. 2024;16(2):eXXXXX.

Muluneh MW, Mulugeta SS, Belay AT, Moyehodie YA. Determinants of low birth weight among newborns at Debre Tabor referral hospital, Northwest Ethiopia: a cross-sectional study. SAGE Open Nurs. 2023;9:23779608231167107.

Mursil M, Rashwan HA, Cavallé-Busquets P, Santos-Calderón LA, Murphy MM, Puig D. Maternal nutritional factors enhance birthweight prediction: a super learner ensemble approach. Information (Basel). 2024;15(11):714.

Islam Pollob SA, Abedin MM, Islam MT, Islam MM, Maniruzzaman M. Predicting risks of low birth weight in Bangladesh with machine learning. PLoS One. 2022;17(5):e0267190.

Shaohua Y, Bin Z, Mei L, Jingfei Z, Pingping Q, Yanping H, et al. Maternal risk factors and neonatal outcomes associated with low birth weight. Front Genet. 2022;13:1019321.

Khazaei Z, Bagheri MM, Goodarzi E, Moayed L, Abadi NE, Bechashk SM, et al. Risk factors associated with low birth weight among infants: a nested case-control study in Southeastern Iran. Int J Prev Med. 2021;12:159.

Ahammed B, Maniruzzaman M, Ferdausi F, Abedin MM, Hossain MT. Socioeconomic and demographic factors associated with low birth weight in Nepal: data from 2016 Nepal demographic and health survey. Asian J Soc Health Behav. 2020;3(4):158-165.

Mizuno S, Nagaie S, Tamiya G, Kuriyama S, Obara T, Ishikuro M, et al. Establishment of early prediction models of low-birth-weight reveals influential genetic and environmental factors: a prospective cohort study. BMC Pregnancy Childbirth. 2023;23(1):628.

Singh D, Manna S, Barik M, Rehman T, Kanungo S, Pati S. Prevalence and correlates of low birth weight in India: findings from National Family Health Survey-5. BMC Pregnancy Childbirth. 2023;23(1):456.

Devaguru A, Gada S, Potpalle D, Eshwar MD, Purwar D. Prevalence of low birth weight among newborn babies and its associated maternal risk factors: a hospital-based cross-sectional study. Cureus. 2023;15(5):eXXXXX.

Bekele WT. Machine learning algorithms for predicting low birth weight in Ethiopia. BMC Med Inform Decis Mak. 2022;22(1):232.

Mansor E, Ahmad N, Mohd Zulkefli NA, Lim PY. Incidence and determinants of low birth weight in Peninsular Malaysia: a multicentre prospective cohort study. PLoS One. 2024;19(7):e0306387.

Dhivar NR, Gandhi R, Murugan Y, Vora H. Outcomes and morbidities in low-birth-weight neonates: a retrospective study from Western India. Cureus. 2024;16(6):eXXXXX.

Mfipa D, Hajison PL, Mpachika-Mfipa F. Predictors of low birthweight and comparisons of newborn birthweights among different groups of maternal factors at Rev. John Chilembwe Hospital, Malawi: a retrospective record review. PLoS One. 2024;19(8):e0291585.

Bansal P, Garg S, Upadhyay HP. Prevalence of low birth weight babies and its association with socio-cultural and maternal risk factors among institutional deliveries in Bharatpur, Nepal. Asian J Med Sci. 2019;10(1):77-85.

Pavanya M, Chadaga K, J V, et al. Prediction of birthweight with early and mid-pregnancy antenatal markers utilising machine learning and explainable artificial intelligence. Sci Rep. 2025;15:26223.

Chen L, Shao H, Zhang J, et al. Developing predictive models for full-term low birth weight infants using ten machine learning algorithms. BMC Pediatr. 2025;25:820.

Mursil M, Rashwan HA, Khalid A, Cavallé-Busquets P, Santos-Calderon L, Murphy MM, et al. Interpretable deep neural networks for advancing early neonatal birth weight prediction using multimodal maternal factors. J Biomed Inform. 2025;166:104838.

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Published

2025-10-31

How to Cite

1.
Dixit S, Prasad J, Saroshe S, Joshi D, Srivastava N. Statistical Modelling for the Assessment of Low Birth Weight in Tertiary Care Settings (2019-2024). Indian Journal of Community Health [Internet]. 2025 Oct. 31 [cited 2026 Feb. 16];37(5):653-8. Available from: http://www.iapsmupuk.org/journal/index.php/IJCH/article/view/3363

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Review Article

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