Risk factors associated with gallstone disease

  • Deepak Dhamnetiya Lady Hardinge Medical College, New Delhi
  • Manish Kumar Goel Lady Hardinge Medical College, New Delhi
  • Balraj Dhiman Lady Hardinge Medical College, New Delhi
  • Om Prakash Pathania Lady Hardinge Medical College, New Delhi
Keywords: Gallstone disease, personal and behavioural risk factors, case-control study


Background: Gallstone disease is one of the most common abdominal conditions for which patients are admitted in surgical wards of hospitals.Aim & Objective: The study was conducted to understand the association between behavioral and personal factors and gall stone disease among study subjects. Settings & Design: a case-control study conducted in a tertiary care hospital of New Delhi. Methods: 120 each of cases and controls of over 20 years, matched for age and sex were recruited in the study. Data collection was done on a self-designed pretested “interview schedule.” Statistical analysis used: The observations have been described in terms of mean, range and standard deviation for continuous data and in terms of percentages/proportions for categorical data. To measure the strength of association simple Odd’s Ratio (OR) was calculated and McNemar’s test was used for matched pair analysis. Independent Student’s‘t’ test was used to study the group difference for quantitative variables. Results: weight (59.20±9.57), height (159.67±6.25), BMI (23.20±3.15), Waist Circumference (75.79±7.07) and W/H ratio (0.80±0.06) were significantly higher [as seen by applying student t test] in cases as compared to controls 54.84±7.02, 156.58±4.93, 21.95±2.81, 73.49±6.09 and 0.77±0.05 respectively. High parity [OR-5.75, 95% CI 1.99-16.63] had the strongest association followed by high W/H ratio  [OR-5.25, 95% CI 1.80-15.29], sedentary physical activity [OR-4.75, 95% CI 2.22-10.18], smoking [OR-3.4, 95% CI 1.25-9.21], consumption of smokeless tobacco [OR-2.36, 95% CI 1.17-4.78] and high BMI [OR-1.71, 95% CI1.03-2.83]. Conclusion: High parity, High W/H ratio, Physical inactivity, Current smoking, Smokeless tobacco and high BMI were found to be risk factors for the development of gallstone disease.

Key Messages: health education to community and masses regarding the benefits of physical activity and avoidance of substance use.


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How to Cite
Dhamnetiya D, Goel M, Dhiman B, Pathania O. Risk factors associated with gallstone disease. Indian J Community Health [Internet]. 24Jun.2018 [cited 19Jul.2018];30(2). Available from: http://www.iapsmupuk.org/journal/index.php/IJCH/article/view/853
Original Article