Assessment of knowledge, attitude, and practices towards hydroxy chloroquine pre-exposure prophylaxis for COVID - 19 among health care professionals.

Published

2020-12-31

DOI:

https://doi.org/10.47203/IJCH.2020.v32i04.012

Keywords:

Hydroxychloroquine, Pre-exposure prophylaxis, Health care professionals, COVID-19

Dimensions Badge

Issue

Section

Original Article

Authors

  • Arpita Singh Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow
  • Hemant Kumar Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow
  • Preeti Gupta Hind Institute of Medical Sciences, Sitapur
  • Ajay Kumar Verma King George’s Medical University, Lucknow, Uttar Pradesh
  • Atul Jain Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow
  • Surya Kant King George’s Medical University, Lucknow https://orcid.org/0000-0001-7520-5404
  • Anuj Kumar Pandey King George’s Medical University, Lucknow https://orcid.org/0000-0002-7403-9800
  • Shivendra Kumar Singh King George’s Medical University, Lucknow

Abstract

Background: There is an urgent need for developing potential drug targets to protect the health care professionals (HCPs) who are at high risk of infection from coronavirus disease-2019 (COVID-19) as they are directly and/ indirectly involved in treatment facility. We aimed to assess knowledge, attitude, and practices towards hydroxychloroquine (HCQ) pre-exposure prophylaxis (PEP) among HCPs directly and/ indirectly involved in COVID-19 treatment. Materials and Methods: This cross-sectional study was multi-centric, and data was collected from HCPs (only doctors and nurses) involved directly or indirectly with COVID-19 patient treatment. The study questionnaire consisted of socio-demographic profile; assessment of HCQ knowledge, attitude, practices, and related adverse drug reactions (ADRs). Results: Of the recruited 374 HCPs, 302 fulfilled the study criteria. Mean age of participants was 33.30 {±standard deviation 7.65}. 64.2% of the participants were male. 16.9% of the individuals (n=51) had co-morbidities. All the HCPs had basic knowledge of COVID-19 and 87.42% were aware of the role of HCQ as PEP. Further, 269 participants (89.07%) were aware that HCQ can cause ADRs.  56.6% participants agreed that HCQ had a protective role against COVID-19 and 54.3 % participants considered that PEP with HCQ had ‘more benefit’ than risk. 52.32% (n=158) HCPs had used HCQ as PEP and 52.53 % (n=83) of these participants had completed the recommended drug course. Twenty participants (12.67%) had experienced ADR, and 12 had reported it to ADR monitoring centre. Conclusion: Our data shows that HCPs are aware of COVID-19 and HCQ prophylaxis. Approximately 57% of the participants agreed that HCQ has a protective role against COVID-19 and 50% of the participants had taken HCQ prophylaxis. Only 12.67% of the participants reported an ADR and in none of them, it was serious enough to discontinue the drug.

How to Cite

1.
Singh A, Kumar H, Gupta P, Verma AK, Jain A, Kant S, Pandey AK, Singh SK. Assessment of knowledge, attitude, and practices towards hydroxy chloroquine pre-exposure prophylaxis for COVID - 19 among health care professionals. Indian J Community Health [Internet]. 2020 Dec. 31 [cited 2022 Oct. 4];32(4):681-7. Available from: https://www.iapsmupuk.org/journal/index.php/IJCH/article/view/1866

Downloads

Download data is not yet available.

Most read articles by the same author(s)