Prevalence of Diabetic Peripheral Neuropathy among Type 2 Diabetes Mellitus patients and its associated risk factors




Diabetic Peripheral Neuropathy, Prevalence, Risk factors, Type 2 DM


Background: Diabetic peripheral neuropathy (DPN) is a common and one of the severe complications of diabetes mellitus. It affects almost half the diabetic population and worsens quality of life of the patient. The present study was aimed to determine the prevalence of peripheral neuropathy and associated risk factors. Aims and Objectives: To assess the Prevalence of Diabetic Peripheral Neuropathy (DPN) among Type 2 DM patients and its associated risk factors. Material and Methods: A community based survey was conducted over a period of one and a half year. Cluster sampling technique was used to collect the study sample in urban Etawah. Study participants aged ? 30 years residing in urban Etawah with known history of Type 2 Diabetes Mellitus of ? 5 years were included in the study. Diabetic Peripheral Neuropathy (DPN) was diagnosed using 10 g monofilament test. Results: A total of 400 DM patients were enrolled in the study. Out of which 28% (n = 112) patients were diagnosed with DPN using Semmes-Weinstein (SW) 10-g monofilament test. Statistically significant association was also noted with Family history of DM, BMI, Systolic and Diastolic blood pressure, Family history of HTN and History of Smoking. Conclusion: The current study found a high prevalence of DPN (28%) and it was found to be significantly associated with advancing age, duration of diabetes and history of smoking.


Download data is not yet available.


Marathe PH, Gao HX, Close KL. American Diabetes Association Standards of Medical Care in Diabetes 2017. Journal of diabetes. 2017;9(4):320-4.

Vinik AI. Diabetic neuropathies. In Controversies in Treating Diabetes 2008:135-156. Humana Pres

Tesfaye S, Chaturvedi N, Eaton SE, Ward JD, Manes C, Ionescu-Tirgoviste C, Witte DR, Fuller JH. Vascular risk factors and diabetic neuropathy. New England Journal of Medicine. 2005;352(4):341-50.

Cameron NE, Eaton SE, Cotter MA, Tesfaye S. Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia. 2001;44(11):1973-88.

Duby JJ, Campbell RK, Setter SM, White JR, Rasmussen KA. Diabetic neuropathy: an intensive review. American Journal of Health-System Pharmacy. 2004;61(2):160-73.

Vinik AI, Mehrabyan A. Diabetic neuropathies. The Medical clinics of North America. 2004;88(4):947-9.

Singh R, Kishore L, Kaur N. Diabetic peripheral neuropathy: current perspective and future directions. Pharmacological research. 2014;80:21-35.8.

Tesfaye S, Boulton AJ, Dyck PJ, Freeman R, Horowitz M, Kempler P, Lauria G, Malik RA, Spallone V, Vinik A, Bernardi L. Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments. Diabetes care. 2010;33(10):2285-93.

DCCT Research Group. Factors in development of diabetic neuropathy: baseline analysis of neuropathy in feasibility phase of Diabetes Control and Complications Trial (DCCT). Diabetes. 1988;37(4):476-81.

Kisozi T, Mutebi E, Kisekka M, Lhatoo S, Sajatovic M, Kaddumukasa M, Nakwagala FN, Katabira E. Prevalence, severity and factors associated with peripheral neuropathy among newly diagnosed diabetic patients attending Mulago hospital: a cross-sectional study. Afr Health Sci. 2017;17(2):463-473.

Sendi RA, Mahrus AM, Saeed RM, Mohammed MA, Al-Dubai SAR. Diabetic peripheral neuropathy among Saudi diabetic patients: A multicenter cross-sectional study at primary health care setting. J Family Med Prim Care. 2020;9(1):197-201.

Mathiyalagen P, Kanagasabapathy S, Kadar Z, Rajagopal A, Vasudevan K. Prevalence and Determinants of Peripheral Neuropathy Among Adult Type II Diabetes Mellitus Patients Attending a Non-communicable Disease Clinic in Rural South India. Cureus. 2021;13(6):e15493.

Jasmine, A., G.V., A., Durai, V. et al. Prevalence of peripheral neuropathy among type 2 diabetes mellitus patients in a rural health centre in South India. Int J Diabetes Dev Ctries 2021;41: 293–300.

Darivemula S, Nagoor K, Patan SK, Reddy NB, Deepthi CS, Chittooru CS. Prevalence and Its Associated Determinants of Diabetic Peripheral Neuropathy (DPN) in Individuals Having Type-2 Diabetes Mellitus in Rural South India. Indian J Community Med. 2019;44(2):88-91.

Gogia S, Rao CR. Prevalence and Risk Factors for Peripheral Neuropathy among Type 2 Diabetes Mellitus Patients at a Tertiary Care Hospital in Coastal Karnataka. Indian J Endocrinol Metab. 2017;21(5):665-669.

Davies M, Brophy S, Williams R, Taylor A. The prevalence, severity, and impact of painful diabetic peripheral neuropathy in type 2 diabetes. Diabetes Care 2006;29:1518-22. [PubMed] [Google Scholar]

Janghorbani M, Rezvanian H, Kachooei A, et al. Peripheral neuropathy in type 2 diabetes mellitus in Isfahan, Iran: prevalence and risk factors. Acta Neurol Scand 2006;114:84-91.

Jarmuzewska EA, Ghidoni A, Mangoni AA. Hypertension and sensorimotor peripheral neuropathy in type 2 diabetes. Eur Neurol. 2007;57(2):91-5.

Mold JW, Vesely SK, Keyl BA, et al. The prevalence, predictors and consequences of peripheral sensory neuropathy in older patients. J Am Board Fam Pract 2004;17:309-18.

Braxton D Mitchell, Victor M Hawthorne, Aaron I Vinik; Cigarette Smoking and Neuropathy in Diabetic Patients. Diabetes Care 1 April 1990; 13 (4): 434–437




How to Cite

Soni K, Srivastava DK, Kumar S, Bajpai PK, Shukla SK, Prakash S. Prevalence of Diabetic Peripheral Neuropathy among Type 2 Diabetes Mellitus patients and its associated risk factors. Indian J Community Health [Internet]. 2024 Apr. 30 [cited 2024 Jul. 24];36(2):208-14. Available from:



Original Article

Most read articles by the same author(s)

1 2 3 > >>