Correlating Substance Abuse Disorders and Mood Disorder: Clinical Implications of a Dimensional Approach

Authors

DOI:

https://doi.org/10.47203/IJCH.2024.v36i03.012

Keywords:

Anxiety, Depression, Substance abuse, GHQ-12, HAM-A, HAM-D

Abstract

Background: Substance use disorder (SUD) often co-occurs with mood disorders like anxiety and depression. This study investigates the relationship between SUD and mood disorders using a dimensional approach. Methods: A total of 290 participants, including 145 with SUD and 145 healthy controls, were assessed. The General Health Questionnaire (GHQ-12) evaluated mental health, followed by interviews using the Hamilton Anxiety Rating Scale (HAM-A) and Hamilton Depression Rating Scale (HAM-D). Demographic information, substance use behaviours, and mental health symptoms were collected and analysed. Results: Of the participants, 90% were men and 10% women; 68.2% were married. Most SUD patients were smokers (71.0%) and alcohol users (35.8%), with others using drugs or tobacco (33.7% and 19.3%). The majority (84.8%) used drugs for a high. HAM-D results showed moderate to severe depression in 7.5% of SUD patients and 5.5% of controls. HAM-A results indicated 80.6% of the SUD group had anxiety, compared to 88.9% of controls with no anxiety. Conclusion: SUD patients frequently experience concurrent anxiety and depression, highlighting the need for dual diagnosis and integrated treatment for SUD and mood disorders.

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References

Ningombam S, Hutin Y, Murhekar MV. Prevalence and pattern of substance use among the higher secondary school students of Imphal, Manipur, India. Natl Med J India. 2011;24(1):11–5.

Grant BF, Stinson FS, Dawson DA, Chou SP, Dufour MC, Compton W, et al. Prevalence and co-occurrence of substance use disorders and IndependentMood and anxiety disorders: Results from the national epidemiologic survey on alcohol and RelatedConditions. Arch Gen Psychiatry [Internet]. 2004;61(8):807-816.

Brooner RK. Psychiatric and substance use comorbidity among treatment-seeking opioid abusers. Arch Gen Psychiatry [Internet]. 1997;54(1):71-80.

Weisner C, Ray GT, Mertens JR, Satre DD, Moore C. Short-term alcohol and drug treatment outcomes predict long-term outcome. Drug Alcohol Depend [Internet]. 2003;71(3):281–94.

Johnson BA, editor. Addiction medicine: Science and practice. New York, NY: Springer New York; 2011.

Mohamed II, Ahmad HEK, Hassaan SH, Hassan SM. Assessment of anxiety and depression among substance use disorder patients: a case-control study. Middle East Curr Psychiatr [Internet]. 2020;27(1):1-8.

Goldberg DP, Hillier VF. A scaled version of the General Health Questionnaire. Psychol Med [Internet]. 1979;9(1):139–45.

Thompson E. Hamilton rating scale for anxiety (HAM-A). Occup Med (Lond) [Internet]. 2015;65(7):601.

Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry [Internet]. 1960;23(1):56–62.

Panebianco D, Gallupe O, Carrington PJ, Colozzi I. Personal support networks, social capital, and risk of relapse among individuals treated for substance use issues. Int J Drug Policy [Internet]. 2016;27:146–53.

Jabeen S, Raja MS, Saeed S, Zafar MM, Ghani RA, Mahmood A, et al. Factors influencing vulnerability towards heroin addiction in a Pakistani cohort. Pak J Zool [Internet]. 2016;49(1):95–9.

Quello SB, Brady KT, Sonne SC. Mood disorders and substance use disorder: a complex comorbidity. Sci Pract Perspect [Internet]. 2005;3(1):13–21.

Cummins SE, Zhu S-H, Tedeschi GJ, Gamst AC, Myers MG. Use of e-cigarettes by individuals with mental health conditions. Tob Control [Internet]. 2014;23 Suppl 3(suppl 3):iii48-53.

Hodgson K, Almasy L, Knowles EEM, Kent JW, Curran JE, Dyer TD, et al. Genome-wide significant loci for addiction and anxiety. Eur Psychiatry [Internet]. 2016;36:47–54.

Pakhtunkhwa P, Naz P, Khan A. The menace of opiate, the socio-psychological and physiological impacts of opiate on addicts in Khyber. Afr J Pharm Pharmacol. 2012;6:1753–64.

Avenevoli S, Stolar M, Li J, Dierker L, Ries Merikangas K. Comorbidity of depression in children and adolescents: models and evidence from a prospective high-risk family study. Biol Psychiatry [Internet]. 2001;49(12):1071–81.

Neale MC, Kendler KS. Models of comorbidity for multifactorial disorders. Am J Hum Genet. 1995;57(4):935–53.

Bellos S, Skapinakis P, Rai D, Zitko P, Araya R, Lewis G, et al. Longitudinal association between different levels of alcohol consumption and a new onset of depression and generalized anxiety disorder: Results from an international study in primary care. Psychiatry Res [Internet]. 2016;243:30–4.

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Published

2024-06-30

How to Cite

1.
Chauhan S, Sharma DD, Siraj SA, Nagrath D, Semwal J. Correlating Substance Abuse Disorders and Mood Disorder: Clinical Implications of a Dimensional Approach. Indian J Community Health [Internet]. 2024 Jun. 30 [cited 2024 Oct. 5];36(3):406-11. Available from: https://www.iapsmupuk.org/journal/index.php/IJCH/article/view/2903

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