Statistical Modelling for the Assessment of Low Birth Weight in Tertiary Care Settings: A Review Article (2019-2024)
Keywords:
Low Birth Weight, Statistical Model, Logistic Regression, Machine Learning, Multiple linear Regression, Bayesian Method, Structural Equation ModelingAbstract
A birth weight less than 2,500 grams defines LBW as a main public health issue both globally and especially in developing nations. It is essential to properly evaluate and manage LBW infants because this practice minimizes newborn health complications. This analysis reviews the application of statistical models (2019-2024) which evaluate risk components and treatment results for LBW cases found in tertiary medical facilities. Research uses logistic regression along with machine learning models in accord to survival analysis to discover maternal indicators along side clinical indicators & socioeconomic indicators that predict LBW. Multiple risk factors are successfully integrated through advanced learning approaches starting from classical regression methods as the review demonstrates. Findings suggest that ensemble methods and deep learning models demonstrate superior predictive performance compared to conventional statistical approaches. The studies indicate that integrating machine learning methods with traditional biostatistics offers a more nuanced understanding of LBW risk. However, the need for interpretable models in clinical settings remains paramount.
Downloads
References
References
Okwaraji YB, Bradley E, Ohuma EO, Yargawa J, Suarez?Idueta L, Requejo J, Blencowe H, Lawn JE. National routine data for low birthweight and preterm births: Systematic data quality assessment for United Nations member states (2000–2020). BJOG: An International Journal of Obstetrics & Gynaecology. 2024 Jun;131(7):917-28.
Mukosha M, Jacobs C, Kaonga P, Musonda P, Vwalika B, Lubeya MK, Mwila C, Mudenda S, Zingani E, Kapembwa KM. Determinants and outcomes of low birth weight among newborns at a Tertiary Hospital in Zambia: A retrospective cohort study. Annals of African Medicine. 2023 Jul 1;22(3):271-8.
Liu Z, Han N, Su T, Ji Y, Bao H, Zhou S, Luo S, Wang H, Liu J, Wang HJ. Interpretable machine learning to identify important predictors of birth weight: A prospective cohort study. Frontiers in Pediatrics. 2022 Nov 11;10:899954.
KC A, Basel PL, Singh S. Low birth weight and its associated risk factors: Health facility-based case-control study. PloS one. 2020 Jun 22;15(6):e0234907.
Gupta S, Jatav P, Saroshe S, Shukla H, Bansal SB. A Cross-Sectional Study to Assess Factors Affecting Low Birth Weight at Tertiary Care Center, Indore. Indian Journal of Public Health Research & Development. 2024 Jul 1;15(3).
Christian P, West KP, Khatry SK, Leclerq SC, Pradhan EK, Katz J, Shrestha SR, Sommer A. Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal2. The American journal of clinical nutrition. 2003 Dec 1;78(6):1194-202.
Thapa P, Poudyal A, Poudel R, Upadhyaya DP, Timalsina A, Bhandari R, Baral J, Bhandari R, Joshi PC, Thapa P, Adhikari N. Prevalence of low birth weight and its associated factors: Hospital based cross sectional study in Nepal. PLOS Global Public Health. 2022 Nov 2;2(11):e0001220.
Mondal B. Risk factors for low birth weight in Nepali infants. The Indian Journal of Pediatrics. 2000 Jul;67:477-82.
Islam MJ, Chowdhury MH, Rahman MM, Rahman Z. Risk factors of children's low birth weight and infant mortality in Bangladesh: Evidence from binary logistic regression and Cox PH models. Health Science Reports. 2024 Aug;7(8):e70009.
Borson NS, Kabir MR, Zamal Z, Rahman RM. Correlation analysis of demographic factors on low birth weight and prediction modeling using machine learning techniques. In2020 Fourth World Conference on Smart Trends in Systems, Security and Sustainability (WorldS4) 2020 Jul 27 (pp. 169-173). IEEE.
Ranjbar A, Montazeri F, Farashah MV, Mehrnoush V, Darsareh F, Roozbeh N. Machine learning-based approach for predicting low birth weight. BMC Pregnancy and Childbirth. 2023 Nov 20;23(1):803.
Wang Q, Gao W, Duan Y, Ren Z, Zhang Y. Exploring predictors of interaction among low-birth-weight infants and their caregivers: a machine learning–based random forest approach. BMC pediatrics. 2024 Oct 10;24(1):648.
Avwerhota OO, Avwerhota M, Daniel EO, Popoola TA, Popoola IO, Ogun AA, Bello AM, Tomori MO, Salami AO, Ekwuluo CE, Alewi OO. Bayesian Spatial Analysis of Risk Factors Affecting Low Birth Weight in Nigeria. Journal of Family Medicine and Health Care. 2024 Aug;10(3):40-50.
Maniragaba VN, Atuhaire LK, Rutayisire PC. Modeling the Risk Factors of Undernutrition among Children below Five Years of Age in Uganda Using Generalized Structural Equation Models. Children. 2023 Dec 14;10(12):1926.
Patterson JK, Thorsten VR, Eggleston B, Nolen T, Lokangaka A, Tshefu A, Goudar SS, Derman RJ, Chomba E, Carlo WA, Mazariegos M. Building a predictive model of low birth weight in low-and middle-income countries: a prospective cohort study. BMC Pregnancy and Childbirth. 2023 Aug 22;23(1):600.
Arabzadeh H, Doosti-Irani A, Kamkari S, Farhadian M, Elyasi E, Mohammadi Y. The maternal factors associated with infant low birth weight: an umbrella review. BMC Pregnancy and Childbirth. 2024 Apr 25;24(1):316.
Bhagat AK, Mehendale AM, Muneshwar KN, Bhagat A. Factors Associated With Low Birth Weight Among the Tribal Population in India: A Narrative Review. Cureus. 2024 Feb 2;16(2).
Muluneh MW, Mulugeta SS, Belay AT, Moyehodie YA. Determinants of low birth weight among newborns at debre tabor referral hospital, Northwest Ethiopia: a cross-sectional study. SAGE Open Nursing. 2023 Mar;9:23779608231167107.
Mursil M, Rashwan HA, Cavallé-Busquets P, Santos-Calderón LA, Murphy MM, Puig D. Maternal Nutritional Factors Enhance Birthweight Prediction: A Super Learner Ensemble Approach. Information. 2024 Nov 6;15(11):714.
Islam Pollob SA, Abedin MM, Islam MT, Islam MM, Maniruzzaman M. Predicting risks of low birth weight in Bangladesh with machine learning. PloS one. 2022 May 26;17(5):e0267190.
Shaohua Y, Bin Z, Mei L, Jingfei Z, Pingping Q, Yanping H, Liping Z, Jiexin Y, Guoshun M. Maternal risk factors and neonatal outcomes associated with low birth weight. Frontiers in genetics. 2022 Sep 28;13:1019321.
Khazaei Z, Bagheri MM, Goodarzi E, Moayed L, Abadi NE, Bechashk SM, Mohseni S, Safizadeh M, Behseresht M, Naghibzadeh-Tahami A. Risk factors associated with low birth weight among infants: A nested case-control study in Southeastern Iran. International journal of preventive medicine. 2021 Jan 1;12(1):159.
Ahammed B, Maniruzzaman M, Ferdausi F, Abedin MM, Hossain MT. Socioeconomic and demographic factors associated with low birth weight in Nepal: Data from 2016 Nepal demographic and health survey. Asian Journal of Social Health and Behavior. 2020 Oct 1;3(4):158-65.
Mizuno S, Nagaie S, Tamiya G, Kuriyama S, Obara T, Ishikuro M, Tanaka H, Kinoshita K, Sugawara J, Yamamoto M, Yaegashi N. Establishment of the early prediction models of low-birth-weight reveals influential genetic and environmental factors: a prospective cohort study. BMC Pregnancy and Childbirth. 2023 Aug 31;23(1):628.
Singh D, Manna S, Barik M, Rehman T, Kanungo S, Pati S. Prevalence and correlates of low birth weight in India: findings from national family health survey 5. BMC Pregnancy and Childbirth. 2023 Jun 20;23(1):456.
Devaguru A, Gada S, Potpalle D, Eshwar MD, Purwar D. The prevalence of low birth weight among newborn babies and its associated maternal risk factors: a hospital-based cross-sectional study. Cureus. 2023 May 5;15(5).
Bekele WT. Machine learning algorithms for predicting low birth weight in Ethiopia. BMC medical informatics and decision making. 2022 Sep 5;22(1):232.
Mansor E, Ahmad N, Mohd Zulkefli NA, Lim PY. Incidence and determinants of low birth weight in Peninsular Malaysia: A multicentre prospective cohort study. Plos one. 2024 Jul 12;19(7):e0306387.
Dhivar NR, Gandhi R, Murugan Y, Vora H. Outcomes and Morbidities in Low-Birth-Weight Neonates: A Retrospective Study From Western India. Cureus. 2024 Jun 8;16(6).
Mfipa D, Hajison PL, Mpachika-Mfipa F. Predictors of low birthweight and comparisons of newborn birthweights among different groups of maternal factors at Rev. John Chilembwe Hospital in Phalombe district, Malawi: A retrospective record review. Plos one. 2024 Aug 29;19(8):e0291585.
Bansal P, Garg S, Upadhyay HP. Prevalence of low birth weight babies and its association with socio-cultural and maternal risk factors among the institutional deliveries in Bharatpur, Nepal. Asian Journal of Medical Sciences. 2019;10(1):77-85.
Published
How to Cite
License
Copyright (c) 2025 Shivam Dixit, Prof (Dr.) Jagdish Prasad, Dr. Satish Saroshe, Dr. Deepa Joshi, Dr. Namita Srivastava

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
